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Depression. Many studies have discovered St. John's wort to be helpful in treating mild to average depression. St. John's wort can treat mild to average depression. Somatic symptom disorder. Some research have discovered that St. John's wort might assist deal with this condition. Triptans. Don't take St. John's wort with these medicines that treat migraines. Photosensitizing medicines. If you're taking St. John's wort with medication that increases sensitivity to sunlight, known as photosensitizing medicine, it would increase the chance of a response. If you're taking St. John's wort with tacrolimus (Prograf, Astagraf XL, others) or cyclosporine (Neoral, Sandimmune, others), it'd lessen the medicine's impact. If you're taking St. John's wort with one of those anti-HIV medicines, it may lessen the medication's effect. If you're taking St. John's wort with this antidepressant, it would lessen the drugs's effect. Barbiturates. If St. John's wort is taken with a drugs that acts as a central nervous system depressant, called a barbiturate, it might lessen the quantity of sleep time the medicine causes.
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